Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer
Nayoung Kim, Sehhoon Park, Areum Jo, Hye Hyeon Eum, Hong Kwan Kim, Kyungjong Lee, Jong Ho Cho, Bo Mi Ku, Hyun Ae Jung, Jong‐Mu Sun, Se‐Hoon Lee, Jin Seok Ahn, Jung-Il Lee, Jung Won Choi, Dasom Jeong, , Myung‐Ju Ahn
This study links tumor and immune cell profiles in NSCLC patients to their response to immune checkpoint inhibitors, finding higher CD4+ regulatory T cells and NF-kB/STAT3 activity in non-responders.
eLife · Nov 8, 2024Peer-reviewedBioinformatics