Alternative Splicing of Apoptosis Genes Promotes Human T Cell Survival
Davia Blake, Caleb M. Radens, Max Ferretti, Matthew R. Gazzara, Kristen W. Lynch
This study shows that CD28 costimulation enhances alternative splicing of apoptosis-related genes, promoting T cell survival through combinatorial effects on caspase-9, Bax, and Bim.
eLife · Oct 20, 2022Peer-reviewedMolecular Biology