Matthew R. Gazzara

The paper improves sQTL modeling by incorporating alternative splicing representation and introduces MAJIQTL, finding new sQTLs linked to Alzheimer's disease.

The paper identifies DDX55 as a novel regulator of 3'UTR isoform diversity through integrative analysis of RNA binding protein depletion experiments.

This study shows RBMX and RBMXL2 proteins regulate splicing of ultra-long exons by repressing cryptic splice sites, with RBMXL2 rescuing splicing defects in somatic cells.

The paper benchmarks eight tools for identifying and quantifying alternative polyadenylation sites from RNA-seq data using real, synthetic, and 3'-end sequencing data.

The paper introduces MAJIQ v2, a tool for analyzing RNA splicing in large and heterogeneous RNA-seq datasets, showing improved performance over existing methods and applying it to brain subregion-specific splicing analysis.

This study shows that CD28 costimulation enhances alternative splicing of apoptosis-related genes, promoting T cell survival through combinatorial effects on caspase-9, Bax, and Bim.

The paper shows RBMX prevents non-productive splicing of ultra-long exons, maintaining genome stability by blocking aberrant splice sites in genes like ETAA1.

The paper analyzes disparities in recognition of computational biology researchers based on gender, name origin, country, and race/ethnicity.

MAJIQ-SPEL is a web-tool that visualizes and quantifies gene isoforms from RNA-Seq data, handling both classical and complex splicing variations and suggesting primers for experimental validation.

The paper identifies antagonistic splicing regulation between CELF2 and RBFOX family proteins in human T cells and shows evolutionary conservation across species.

This paper improves AS prediction models by integrating diverse data sources and introduces a new target function that enhances model accuracy.