Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia
Judith Allardyce, Ganna Leonenko, Marian L. Hamshere, Antonio F. Pardiñas, Liz Forty, Sarah Knott, Katherine-Gordon Smith, David J. Porteus, Caroline Haywood, Arianna Di Florio, Lisa Anne Jones, Andrew Mark McIntosh, Michael John Owen, Peter Holmans, James Walters, , Valentina Escott‐Price
The paper investigates the relationship between polygenic risk scores for schizophrenia and psychotic features in bipolar disorder, finding a gradient of genetic liability based on the level of mood-incongruent symptoms.
bioRxiv · Sep 19, 2017 · PreprintGenetics