Author

David M. Hart

East Carolina University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:behavioral assay· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Aidan C. Charles· 2 shared Benjamin M. Brisard· 2 shared Cameron A. SchmidtiD· 2 shared Debajit BhowmickiD· 2 shared Heather A. BelcheriD· 2 shared Paul W. VosiD· 2 shared Aishwarya P Halder· 1 shared Amy L. Ward· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Aidan C. Charles

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Losing the split ends: unraveling the mechanisms of fiber branching during blood clot formation

Aravind Elangovan, Dylan M. Miller, Can Cai, Key Crosley, Heather A. Belcher, Rachel Lee, Chad Michael Hobson, David M. Hart, Martin Guthold, Brittany E. Bannish, Nathan E. Hudson

This study uses advanced microscopy to observe fibrin fiber branching during clot formation, revealing that branching occurs through mature fiber binding rather than splitting or protofibril association.

bioRxiv · Oct 19, 2026 · PreprintBiophysics

Compositional Analysis of Mouse Sperm Subpopulations During Capacitation In Vitro

Benjamin M. Brisard, Aishwarya P Halder, Aidan C. Charles, Amy L. Ward, Maryam Asadi, David M. Hart, Debajit Bhowmick, Paul W. Vos, Cameron A. Schmidt

This study uses single-cell flow cytometry and statistical modeling to analyze how mouse sperm subpopulations change during capacitation in vitro, revealing nonlinear interactions between bicarbonate and calcium.

bioRxiv · Dec 25, 2025 · PreprintCell Biology

Modeling Diffusive Search by Non-Adaptive Sperm: Empirical and Computational Insights

Benjamin M. Brisard, Kylie D. Cashwell, Stephanie M. Stewart, Logan M. Harrison, Aidan C. Charles, Chelsea V. Dennis, Ivie R. Henslee, Ethan L. Carrow, Heather A. Belcher, Debajit Bhowmick, Paul W. Vos, M. Majka, Martin Bier, David M. Hart, Cameron A. Schmidt

This paper models sperm movement as a diffusive search process and develops computational models to explore how sperm motility and microenvironmental factors influence fertilization success.

PLoS Computational Biology · Apr 17, 2025Peer-reviewedCell Biology