mTORC1 activates PASK-Wdr5 signaling to epigenetically connect the nutrient status with myogenesis.
Chintan K. Kikani, Xiaoying Wu, Sarah Fogarty, Seong Anthony Woo Kang, Noah Dephoure, Steve Gygi, David Sabatini, Jared Rutter
The paper shows mTORC1 activates PASK-Wdr5 signaling to epigenetically link nutrient status with myogenesis by promoting Myogenin transcription and differentiation.
bioRxiv · Dec 10, 2017 · PreprintCell Biology