Simulation-guided non-thermal low-intensity ultrasound reprograms the tumor immune microenvironment and engages systemic antitumor immunity in a syngeneic orthotopic mouse model of breast cancer
Reyhaneh Hooshmandabbasi, Ali Kazemian, Rahul Singha, Manuel Vielma, Niloufar Nikkhah Bahrami, Thomas Hauser, Mathias Sebastian Weyland, Franco Guscetti, David Wahl, Daniel Fehr, Mathias Bonmarin, Stephan Scheidegger, Caroline Maake
This paper investigates the effects of non-thermal low-intensity ultrasound on tumor biology and immune response in a mouse breast cancer model, showing reduced tumor growth and immune system activation.
bioRxiv · Aug 18, 2026 · PreprintCancer Biology