Oral bioavailability of a noncoding RNA drug, TY1, that acts on macrophages
Shukuro Yamaguchi, Kazutaka Miyamoto, Xaviar Michael Jones, Alessandra Ciullo, Kara Tsi, Jessica Anderson, Hiroaki Komuro, Salwa Soussi, Ashley Anne Morris, Diána Kitka, De-Zhao Liu, Nguyễn Thị Vân Anh, Eduardo Marbán, Ahmed Gamal-Eldin Ibrahim
This paper demonstrates an orally bioavailable formulation of a noncoding RNA drug, TY1, which targets macrophages and shows therapeutic benefits in two tissue injury models.
Journal of Extracellular Biology · Aug 1, 2025Peer-reviewedSynthetic Biology