Guanine-nucleotide Exchange Modulator, GIV/Girdin, Serves as a Tunable Valve for Growth Factor-Stimulated Cyclic AMP Signals
Michael Getz, Lee Swanson, Debashish Sahoo, Pradipta Ghosh, Padmini Rangamani
The paper presents a network-based model of GIV/Girdin-dependent cAMP signaling, revealing its role as a tunable control valve distinct from GPCRs and PDEs.
bioRxiv · Jul 13, 2018 · PreprintSystems Biology