Michael Getz

V-Cornea models corneal epithelium homeostasis, injury, and recovery, accurately predicting healing times and structural changes following trauma or chemical exposure.

The paper introduces a framework for mathematical modeling of multicellular systems using interpretable cell behavior rules derived from biological knowledge and multi-omics data.

The paper develops a multiscale mathematical model of immune surveillance in micrometastases to simulate patient trajectories and identify key parameters affecting immunosurveillance outcomes.

The paper develops computational models of the Ca2+/cAMP pathway and AKAP/AC nanodomains, predicting incoherent feedforward loop behavior in Ca2+/cAMP oscillations.

Open-source agent-based PhysiCell model of SARS-CoV-2 infection in lung epithelium; version 5 clears virus in about 6 days in simulation, and delayed T cell arrival increases epithelial loss.

The paper presents a network-based model of GIV/Girdin-dependent cAMP signaling, revealing its role as a tunable control valve distinct from GPCRs and PDEs.