LINE-1 ORF1p is a shared and immunogenic antigen in cancer
Wilson McKerrow, Megan Snyder, Chong Chu, Deena Kelly, Heike Keilhack, Liyang Diao
This study identifies LINE-1 ORF1p as a shared and immunogenic antigen in cancer, showing its expression in tumors, MHC class I presentation, and in vitro immunogenicity.
bioRxiv · Jun 11, 2025 · PreprintCancer Biology