Dehydration promotes intracellular lipid synthesis and accumulation
Joshua Carty, Jazlyn A. Selvasingh, Yvonne P. Zuchowski, Hyuck-Jin Nam, Clothilde Pénalva, Gayani Nanayakkara, Erin Q. Jennings, Kelsey Voss, Edith T. Adame, John T. Tossberg, Wei Sheng Yap, Meiling Melzer, Olga M. Viquez, A. Scott McCall, Elizabeth R. Piotrowski, , Juan Pablo Arroyo
This study shows dehydration increases intracellular lipid synthesis and accumulation by promoting glutamine oxidation and mitochondrial metabolic remodeling.
Nature Communications · May 25, 2026Peer-reviewedPhysiology