Protective role of Pten downregulation in Huntington's Disease models
Nisha Nisha, Deepti Thapliyal, Bhavya Gohil, Aninda Sundar Modak, Sanchi Ahuja, N. Tarundas Singh, Bhavani Shankar Sahu, Mayanglambam Dhruba Singh
This study shows that downregulating Pten improves HD symptoms in fly and cell models by reducing aggregates and apoptosis.
bioRxiv · Mar 28, 2024 · PreprintNeuroscience