Shipment Stress in Early Life Aggravates Disease Pathogenesis in Mice with Experimental Autoimmune Encephalomyelitis: Support for a Two-Hit Hypothesis of Multiple Sclerosis Etiology
Jamshid Faraji, Dennis Bettenson, Voon Wee Yong, Gerlinde A. S. Metz
This study shows that early life stress from animal transportation worsens experimental autoimmune encephalomyelitis in mice, supporting a two-hit model for multiple sclerosis etiology.
Journal of Neuroimmunology · Nov 6, 2023Peer-reviewedNeuroscience