A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system
Kathleen Grabert, Anuj Sehgal, Katharine M. Irvine, Evi Wollscheid-Lengeling, Derya D. Ozdemir, Jennifer Stables, Garry A. Luke, Martin D. Ryan, Antony Adamson, Neil E. Humphreys, Cheyenne J. Sandrock, Rocio Rojo, Veera A. Verkasalo, Werner Mueller, Peter Hohenstein, , David A. Hume
This paper develops a CSF1R-FRed transgenic mouse that specifically labels mononuclear phagocyte system cells, showing high expression in monocytes, macrophages, and dendritic cells while excluding other lineages.
The Journal of Immunology · Dec 1, 2020Peer-reviewedImmunology