Kathleen Grabert

This study examines how reduced Ciita levels affect immune responses in a rat model of Parkinson's disease, finding increased TNF levels and altered MHCII expression in immune cells.

This study investigates a kinase-dead Csf1r mutation in mice, showing it causes dominant-negative effects on CSF1R signaling and impacts macrophage development and brain microglia.

This study identifies Arg1+ microglia as a distinct subtype in female mice, showing their role in cognitive function through dendritic spine maturation and behavior.

This paper develops a CSF1R-FRed transgenic mouse that specifically labels mononuclear phagocyte system cells, showing high expression in monocytes, macrophages, and dendritic cells while excluding other lineages.

The paper reports a CRISPR-Cas9-induced deletion and reinsertion event in the mouse Csf1r promoter, highlighting the need for copy number analysis to confirm genomic edits.