A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa
Maxine S. Harlemon, Olabode Ajayi, Paidamoyo Kachambwa, Michelle S. Kim, Corinne Simonti, Melanie H. Quiver, Desiree C. Petersen, Anuradha Mittal, Pedro W. Fernandez, Ann W. Hsing, Shakuntala Baichoo, Ilir Agalliu, Mohamed Jalloh, Sérigne Maguèye Gueye, Nana Yaa Snyper, , Joseph Lachance
The paper develops a genotyping array tailored for African populations to identify cancer risk variants, finding population-specific allele frequency differences and lower prostate cancer risk in Senegal compared to Nigeria.
Cancer Research · May 11, 2020Peer-reviewedGenomics