Alfred I. Neugut

A generalizable cross-continent prediction of esophageal squamous cell carcinoma using the oral microbiome

This study develops a machine learning model using oral microbiome data to predict esophageal squamous cell carcinoma, showing good performance across different geographic regions.

Pre-clinical validation of an RNA-based precision oncology platform for patient-therapy alignment in a diverse set of human malignancies resistant to standard treatments

The paper validates an RNA-based platform for predicting drug sensitivity in treatment-resistant cancers using patient-derived xenograft models and multi-protein therapies.

A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa

The paper develops a genotyping array tailored for African populations to identify cancer risk variants, finding population-specific allele frequency differences and lower prostate cancer risk in Senegal compared to Nigeria.