Pervasive chromothripsis drives pleural mesothelioma to impact gene function and patient survival
Colin Semple, Kitty Sherwood, Stuart Aitken, Ryan Silk, Mihail Halachev, Stephen Fox, Devin Bendixsen, Alhafidz Hamdan, Kevin G Blyth
This study identifies chromothripsis as a common driver of pleural mesothelioma, linked to gene deletions and poor patient survival.
bioRxiv · Nov 4, 2026 · PreprintCancer Biology