Targeted RNA editing by direct delivery of an adenosine deaminase-antisense oligo conjugate
Tanner W. Eggert, Dhruv Y. Dhingani, Ralph E. Kleiner
This paper develops a method for targeted RNA editing using a covalent adenosine deaminase-antisense oligo conjugate, achieving efficient and specific A-to-I editing with reduced off-target effects.
bioRxiv · Jul 11, 2025 · PreprintBiochemistry