Glucocorticoids rapidly modulate CaV1.2-mediated calcium signals through Kv2.1 channel clusters in hippocampal neurons
Di Wan, Tongchuang Lu, Chenyang Li, Changlong Hu
This study shows glucocorticoids rapidly reduce Kv2.1 and CaV1.2 surface expression in hippocampal neurons, decreasing Ca2+ spikes through endocytosis of Kv2.1 clusters and reduced PKA activity.
Journal of Neuroscience · Sep 19, 2024Peer-reviewedNeuroscience