Methods to study toxic transgenes in C. elegans: an analysis of protease-dead separase in the C. elegans embryo
Diana M Mitchell, Lindsey R Uehlein, Joshua Bembenek
This paper develops two methods to study dominant-negative transgenes in C. elegans embryos, specifically protease-dead separase, overcoming the issue of transgene-induced lethality.
bioRxiv · Feb 6, 2014Cell Biology