Prenatal alcohol exposure promotes nerve injury-induced pathological pain following morphine treatment via NLRP3-mediated peripheral and central proinflammatory immune actions.
Andrea A Pasmay, Ariana N Pritha, Justin R. Carter, Alissa Jones, Annette K. Fernandez-Oropeza, Melody S. Sun, Diane C. Jimenez, Minerva Murphy, Carlos Fernando Valenzuela, Shahani Noor
This study shows prenatal alcohol exposure enhances morphine-induced pathological pain through NLRP3-mediated proinflammatory immune responses in nerve-injured mice.
Brain Behavior and Immunity · Jul 6, 2025Peer-reviewedNeuroscience