Author

Diego Acosta-Alvear

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Adrien Le Thomas· 1 shared Alvin Gogineni· 1 shared Amy Heidersbach· 1 shared Avi AshkenaziiD· 1 shared Benjamin Haley· 1 shared Daniel W Sherbenou· 1 shared David A Lawrence· 1 shared David Kan· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adrien Le Thomas

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1 paper

Recent·Most cited

Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

Jonathan M Harnoss, Adrien Le Thomas, Scot A Marsters, David A Lawrence, Min Lu, Yung-Chia Ariel Chen, Jing Qing, Klara Totpal, David Kan, Ehud Segal, Heidi Ackerly Wallweber, Weiru Wang, Kevin Clark, Susan Kaufman, Maureen Beresini, , Avi Ashkenazi

This study shows that disrupting IRE1α's kinase domain reduces multiple myeloma tumor growth and enhances treatment efficacy, suggesting it as a therapeutic target.

bioRxiv · Dec 14, 2018 · PreprintCancer Biology