Dengue serotype-1 virus like particles induce antibody responses following HeLa cell expression
Smita Shrestha, Archana Maharjan, Roji Raut, Binod Manandhar, Binod Khadka, Ajit Poudel, Tek Raj Joshi, Dilip Chaurasia, Saugat R.C, Jarina Joshi, Rajani Malla, Lata Karki, Ram Prasad Aganja, Rajindra Napit, Krishna Das Manandhar
This study produces Dengue-1 virus-like particles in HeLa cells that induce strong antibody responses in mice, suggesting their potential as a vaccine candidate and serodiagnostic tool.
bioRxiv · Apr 10, 2026 · PreprintImmunology