Identification of unusually disulphide-bonded insulin forms using mass spectrometry and thermolysin cleavage
Dillon Jevon, Kyung‐Mee Moon, Leonard J. Foster, James D. Johnson
The paper presents a method to identify disulphide-bonded insulin forms using thermolysin cleavage and LC-MS/MS, revealing aberrant species linked to diabetes.
bioRxiv · Mar 11, 2022 · PreprintMolecular Biology