Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction
Thomas J. Hoffmann, Rebecca E. Graff, Ravi Madduri, Alex A Rodriguez, Clinton L. Cario, Kun-Jiang Feng, Yu Jiang, Anqi Wang, Robert J. Klein, Brandon L. Pierce, Scott E. Eggener, Tong Lin, William J. Blot, Jirong Long, Louisa B. Goss, , John S. Witte
This study identifies 447 new genetic variants associated with prostate-specific antigen levels across multiple ancestries and shows improved cross-ancestry prediction of PSA, with implications for personalized prostate cancer screening.
medRxiv · Oct 27, 2023 · PreprintGenetic & Genomic Medicine