Author

Dinesh Manandhar

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ami M. KabadiiD· 1 shared Amy SchmidiD· 1 shared Barbara Elizabeth EngelhardtiD· 1 shared Charles A. GersbachiD· 1 shared Christopher M. VockleyiD· 1 shared Gregory E. CrawfordiD· 1 shared Ian C. McDowelliD· 1 shared Jennifer B. Kwon· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Ami M. KabadiORCID

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2 papers

Recent·Most cited

Clustering gene expression time series data using an infinite Gaussian process mixture model

Ian C. McDowell, Dinesh Manandhar, Christopher M. Vockley, Amy Schmid, Timothy E. Reddy, Barbara Elizabeth Engelhardt

This paper introduces a nonparametric model, DPGP, to cluster gene expression time series data and demonstrates its effectiveness using simulated and real datasets.

PLoS Computational Biology · Jan 16, 2018Peer-reviewedBioinformatics

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

Dinesh Manandhar, Lingyun Song, Ami M. Kabadi, Jennifer B. Kwon, Lee Edsall, Melanie Ehrlich, Koji Tsumagari, Charles A. Gersbach, Gregory E. Crawford, Raluca Gordân

The paper quantifies incomplete gene expression and chromatin accessibility changes during MyoD-induced transdifferentiation of human fibroblasts into myoblasts, linking chromatin remodeling deficiencies to incomplete reprogramming.

Nucleic Acids Research · Aug 28, 2017Peer-reviewedGenomics