Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies
Dinesh Manandhar, Lingyun Song, Ami M. Kabadi, Jennifer B. Kwon, Lee Edsall, Melanie Ehrlich, Koji Tsumagari, Charles A. Gersbach, Gregory E. Crawford, Raluca Gordân
The paper quantifies incomplete gene expression and chromatin accessibility changes during MyoD-induced transdifferentiation of human fibroblasts into myoblasts, linking chromatin remodeling deficiencies to incomplete reprogramming.
Nucleic Acids Research · Aug 28, 2017Peer-reviewedGenomics