mRNA structural dynamics shape Argonaute-target interactions
Suzan Ruijtenberg, Stijn Sonneveld, Tao Ju Cui, Ive Logister, Dion de Steenwinkel, Yao Xiao, Ian J. MacRae, Chirlmin Joo, Marvin E. Tanenbaum
The paper develops a live-cell imaging assay to study how mRNA structures affect AGO2-siRNA interactions and mRNA degradation.
Nature Structural & Molecular Biology · Jul 13, 2020Peer-reviewedMolecular Biology