Investigation of sterile hydrogels as topical vehicles for APOSEC™, a stressed peripheral blood mononuclear cell secretome for the treatment of poorly healing wounds
Dalia Hamid, Lisa Auer, Stefan Mohr, Sylwia Gazda-Miarecka, Melanie Salek, Hannes Kühtreiber, Nina Langoth-Fehringer, Tanja Pfleger, Victoria Klang, Michael Mildner, Clemens Aigner, Dirk Sorgenfrey, Hendrik Jan Ankersmit, Lea Ann Dailey, Gianluca Bello
This study evaluates a hydrogel-based delivery system for APOSEC™ in wound healing, finding improved release but non-uniform mixing and no significant efficacy difference compared to a benchmark gel.
International Journal of Pharmaceutics · Apr 30, 2026Peer-reviewedPharmacology & Toxicology