17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice
Louis Saddic, Sean S. Escopete, Lior Zilberberg, Shannon Kalsow, Divya Gupta, Mansoureh Eghbali, Sarah J. Parker
This study shows that 17 β-estradiol reduces aortic root dilation and improves survival in Marfan male mice by inhibiting TNF-NF-κB signaling and preventing aortic smooth muscle cell inflammation.
International Journal of Molecular Sciences · Sep 1, 2023Peer-reviewedGenetics