Mansoureh Eghbali

Radiation-Induced Cellular Plasticity: A Strategy for Combatting Glioblastoma

This study shows that combining radiation with forskolin induces a differentiation-like state in glioma cells, reducing proliferation and extending survival in mouse models.

17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice

This study shows that 17 β-estradiol reduces aortic root dilation and improves survival in Marfan male mice by inhibiting TNF-NF-κB signaling and preventing aortic smooth muscle cell inflammation.

Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension

The paper identifies a gene co-expression module, the pink module, associated with PAH severity, genetic risk, vascular cell types, and therapeutic targets through multiomics integration.

A Tm4sf1-Marked Subpopulation of Endothelial Stem/Progenitor Cells Identified by Lung Single-Cell Omics of Pulmonary Arterial Hypertension

The paper identifies a Tm4sf1-marked endothelial stem/progenitor cell subpopulation in rat lungs associated with PAH and shows its relevance to human PAH through transcriptomic analysis.