Curvature-dependent morphological reorganization of the endoplasmic reticulum determines the mode of epithelial migration
Simran Rawal, Pradeep Keshavanarayana, Diya Manoj, Purnati Khuntia, Sanak Banerjee, Basil Thurakkal, Rituraj Marwaha, Fabian Spill, Tamal Das
The paper shows that endoplasmic reticulum (ER) morphology changes with edge curvature in epithelial gaps, supporting different migration modes through focal adhesion orientation.
bioRxiv · Apr 22, 2025 · PreprintCell Biology