Fabian Spill

The paper develops a mechanistically derived model of SLC25A10 transport, incorporating competitive binding and electroneutrality, and validates it with experimental data.

This paper develops a computational model to study how cancer cells interact with and remodel the extracellular matrix, revealing how structural and chemical cues influence invasion.

The paper shows that endoplasmic reticulum (ER) morphology changes with edge curvature in epithelial gaps, supporting different migration modes through focal adhesion orientation.

This study uses a hybrid computational model to show that increased ECM stiffness inhibits invasion in aggressive cancer cells but not in non-invasive ones.

This study uses a mathematical model to explore how chromaffin cells maintain electron transport chain function despite SDH-b loss, revealing mechanisms that support cell survival.

This study develops a mathematical model of p53's role in reversing the Warburg effect by modulating cancer metabolism, showing that p53 activation can restore OXPHOS and that targeting glycolysis may be more effective than targeting SCO2 in p53-mutated cancers.

This study shows that pyruvate from bone marrow mesenchymal stem cells supports myeloma cell redox homeostasis and anabolism through MCT-1/2 transporters.

The paper develops an integrated in silico and 3D in vitro model to study how tumor microenvironment factors influence macrophage migration and cancer invasion.