Mitochondria-nucleus communication dictates progressive versus bimodal aging of the mammary gland.
Edmund Charles Jenkins, Mrittika Chattopadhyay, Thelma Mashaka, Dmitry Polushakov, Miguel Torres-Martin, Daniela Sia, Igor L. Bado, Doris Germain
The paper shows that mitochondria-nucleus communication in mice leads to bimodal mammary gland aging patterns linked to breast cancer susceptibility.
bioRxiv · Jan 25, 2026 · PreprintCancer Biology