Inhibitor of apoptosis proteins determine glioblastoma stem-like cells fate depending on oxygen level
Aurélie Soubéran, Jessica Cappaï, Mathieu Chocry, Christopher Nuccio, Julie Raujol, Carole Colin, Daniel Lafitte, Hervé Kovacic, Véronique Quillien, Nathalie Baeza-Kallee, Geneviève Rougon, Dominique Figarella-Branger, Aurélie Tchoghandjian
This study investigates how IAP inhibitors affect glioblastoma stem-like cells under hypoxic and normoxic conditions, showing differential effects on apoptosis, proliferation, and differentiation.
bioRxiv · Feb 2, 2018 · PreprintCancer Biology