Quantitative proteomic alterations of human iPSC-based neuronal development indicate early onset of Rett syndrome.
Suzy Varderidou‐Minasian, Lisa Hinz, Dominique Hagemans, Daniëlle Posthuma, Maarten A. F. Altelaar, Vivi Majella Heine
The paper uses proteomic analysis of iPSC-derived neurons to identify early molecular changes in Rett syndrome, showing altered protein expression before symptoms appear.
bioRxiv · Apr 10, 2019 · PreprintNeuroscience