Bacillus Calmette-Guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation
Christine Deffert, Michela G. Schäppi, Jean-Claude Pache, Julien Cachat, Dominique Vesin, Ruth Bisig, Xiaojuan Ma Mulone, Tiina Kelkka, Rikard Holmdahl, Irene Garcia, Maria L. Olleros, Karl-Heinz Krause
This study shows that NADPH oxidase deficiency in CGD mice leads to severe BCG infection due to increased cytokine production and impaired granuloma formation.
PLoS Pathogens · Sep 4, 2014Peer-reviewedMicrobiology