Shotgun metagenomic analysis of the oral microbiomes of children with noma reveals a novel disease-associated organism
Michael Olaleye, Angus M. O’Ferrall, Richard N. Goodman, Deogracia Wa Kabila, Miriam Peters, Grégoire Falq, Joseph Samuel, Donal Doyel, Diana I. Gomez, Gbemisola Oloruntuyi, Shafi’u Isah, Adeniyi Semiyu Adetunji, Elise Farley, Nicholas J. Evans, Mark Sherlock, , Stuart Ainsworth
This study uses shotgun metagenomic analysis of oral saliva from children with noma to identify Treponema sp. A as a novel disease-associated organism and highlights antimicrobial resistance concerns.
bioRxiv · Jun 24, 2025 · PreprintPathology