Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle
Bradley A. Ruple, Joshua S. Godwin, Paulo H. C. Mesquita, Shelby C. Osburn, Christopher G. Vann, Donald A. Lamb, Casey L. Sexton, Darren Glenn Candow, Scott C. Forbes, Andrew D. Frugé, Andreas N. Kavazis, Kaelin C. Young, Robert A. E. Seaborne, Adam Philip Sharples, Michael D. Roberts
Resistance training reduces methylation at 63% of mtDNA CpG sites in older males, mimicking a youthful methylome signature and enhancing mitochondrial function.
The FASEB Journal · Aug 23, 2021Peer-reviewedMolecular Biology