Andreas N. Kavazis

Exogenous L6 myotube mitochondrial transplantation attenuates hypertrophy and elicits a unique proteomic signature in phenylephrine-treated H9C2 cardiomyocytes

This study shows that transplanting L6 myotube mitochondria reduces hypertrophy and alters proteomic pathways in phenylephrine-treated H9C2 cardiomyocytes.

Acute molecular and chronic vastus lateralis adaptations to lengthened partial versus full range of motion resistance training in previously trained males

This study compares acute and chronic adaptations in vastus lateralis muscle from lengthened partial versus full range of motion resistance training in trained males, finding similar outcomes but potential hamstring differences.

Skeletal muscle mitochondrial responses to a single bout and six weeks of high load versus high volume resistance training in previously trained men

This study compares mitochondrial mRNA and protein responses to high-load and high-volume resistance training in trained men, finding no differences between the two training paradigms.

Resistance Exercise and Mechanical Overload Upregulate Vimentin for Skeletal Muscle Remodeling

The paper investigates how resistance exercise and mechanical overload upregulate vimentin in skeletal muscle, linking it to hypertrophy and regeneration.

Skeletal muscle myosin heavy chain protein fragmentation as a potential marker of protein degradation in response to resistance training and disuse atrophy

This study examines how resistance exercise and disuse atrophy affect myosin heavy chain (MyHC) protein fragmentation in humans, finding increased fragmentation post-exercise and during atrophy, with adaptive responses after training.

Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training

This study examines how resistance training before endurance training affects mitochondrial adaptations, finding that prior resistance training impairs mitochondrial responses to subsequent endurance training.

Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men

This study compares DNA methylation and mRNA responses to lower- versus higher-load resistance exercise in trained men, finding similar gene expression and methylation patterns despite differences in exercise intensity.

Resistance training rejuvenates the mitochondrial methylome in aged human skeletal muscle

Resistance training reduces methylation at 63% of mtDNA CpG sites in older males, mimicking a youthful methylome signature and enhancing mitochondrial function.

Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy

This study examines how high-volume resistance training affects muscle fiber hypertrophy and metabolic adaptations in trained men, finding increased sarcoplasmic protein and decreased actin/myosin concentrations.