Shelby C. Osburn

This study examines how resistance training before endurance training affects mitochondrial adaptations, finding that prior resistance training impairs mitochondrial responses to subsequent endurance training.

This study compares DNA methylation and mRNA responses to lower- versus higher-load resistance exercise in trained men, finding similar gene expression and methylation patterns despite differences in exercise intensity.

Resistance training reduces methylation at 63% of mtDNA CpG sites in older males, mimicking a youthful methylome signature and enhancing mitochondrial function.

This study examines how high-volume resistance training affects muscle fiber hypertrophy and metabolic adaptations in trained men, finding increased sarcoplasmic protein and decreased actin/myosin concentrations.