The SARS-CoV-2 nonstructural protein 15 collapses the host cytoskeleton by interacting with the host keratin type II cytoskeletal 1
Donald Tam, César U. Monjarás-Ávila, Hans H. Adomat, Horacio Bach
This study identifies NSP15 as a SARS-CoV-2 protein that interacts with host keratin type II cytoskeletal 1, leading to cytoskeletal collapse and reduced cell viability in Vero E6 cells.
bioRxiv · Dec 29, 2025 · PreprintMicrobiology