Chlamydia-induced ex vivo activation of B cells from mice, nonhuman primates, and humans produces large numbers of uniformly activated antigen presenting cells
Rodolfo D. Vicetti Miguel, Joseph G. Charek, Shumin Fan, Dondrae J Coble, Nirk E. Quispe Calla, Thomas L. Cherpes
The paper shows Chlamydia activates B cells across species to become APCs that elicit strong T cell immunity against pathogens and tumors.
bioRxiv · Jul 25, 2025 · PreprintImmunology