Microvilli regulate the release modes of alpha-tectorin to organize the domain-specific matrix architecture of the tectorial membrane.
Ava Niazi, Ju Ang Kim, Dong-Kyu Kim, Di Lu, Igal Sterin, Joosang Park, Sungjin Park
The paper identifies two distinct release modes of alpha-tectorin (TECTA) mediated by microvilli and proteolytic shedding, which determine domain-specific matrix organization in the tectorial membrane.
bioRxiv · Jan 4, 2024 · PreprintDevelopmental Biology