Inhibition of release of intestinal extracellular vesicles in Ascaris suum and immune modulation by the anthelminthic, ivermectin
Dongjie Liu, Paul Williams, Michael J. Kimber, Alan Patrick Robertson, Richard J. Martin
This study shows ivermectin inhibits intestinal extracellular vesicle release in Ascaris suum and modulates immune-related proteins in these vesicles, with an IC50 of 64 nM.
bioRxiv · Aug 28, 2026 · PreprintPharmacology & Toxicology