Richard J. Martin

This study shows ivermectin inhibits intestinal extracellular vesicle release in Ascaris suum and modulates immune-related proteins in these vesicles, with an IC50 of 64 nM.

This paper identifies β-alanine betaine as an endogenous ligand for specific nicotinic receptors in Ascaris suum, suggesting it could be a novel target for anthelmintic drug development.

This paper introduces a method using post-glycosylation modifying enzymes to visualize specific PGMs in tissue N-glycans via mass spectrometry imaging.

The paper uses blood-based RNA-Seq on 5,412 individuals with rare diseases to identify new candidate diagnoses and shows its utility in prioritizing genetic variants.

This study identifies GoSlo-SR-5-69 as a positive allosteric modulator that enhances emodepside's potency against Brugia malayi SLO-1 K channels.