Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leukocyte antigen locus
Tom Parks, Katherine S. Elliott, Theresa L. Lamagni, Kathryn Auckland, Alexander J. Mentzer, Rebecca L. Guy, Doreen Cartledge, Lenka Strakova, Daniel O’ Connor, Andrew John Pollard, Matthew Neville, Anubha Mahajan, Houman Ashrafian, Stephen Jonathan Chapman, Adrian V. S. Hill, , Julian Charles Knight
The paper identifies an association between the HLA-DQA1*01:03 allele and increased risk of invasive group A streptococcal disease using case-control studies and HLA imputation.
Genes and Immunity · Aug 28, 2019Peer-reviewedGenetics