Conjugative transfer inhibition of IncA and IncC plasmids by pervasive SGI1-like elements via relaxosome assembly interference
Florence Deschênes, Romain Durand, Kevin T. Huguet, Nicolas Rivard, Chloé Chagnon, Doriane Planez, Antoine Lévénès, Vincent Burrus
This study identifies CtiC, a fertility inhibitor encoded by SGI1 that blocks conjugative transfer of IncA/C plasmids by interfering with relaxosome assembly.
Nucleic Acids Research · Sep 22, 2026Peer-reviewedMicrobiology